Risk factors for chronic renal failure are:
1. The duration of the risk factors of chronic renal failure progressive development, including high blood sugar control are not satisfied, hypertension, proteinuria (including microalbuminuria), hypoalbuminemia, and smoking. In addition, a small number of studies suggest that anemia, hyperlipidemia, Hyperhomocysteinemia, malnutrition, elderly, uremic toxins (such as methyl guanidine, parathyroid hormone, phenols) accumulation, etc., may also be in progression of chronic renal failure may play a role, needs further study.
2. In the course of one stage of chronic renal failure, acute exacerbation of renal function may occur, and sometimes can progress to end-stage, or even threaten the lives of patients. The main risk factor for acute exacerbations are:
① involving kidney disease (such as primary glomerulonephritis, hypertension, diabetes, ischemic nephropathy) recurrence or worsening;
② hypovolemia (low blood pressure, dehydration, bleeding or shock, etc.);
③ kidney for drastically reduced local blood (such as renal artery stenosis in patients ACEI, ARB and other drugs);
④ failed to control severe hypertension;
⑤ nephrotoxic drugs;
⑥ urinary tract obstruction;
⑦ severe infection;
⑧ Other: hypercalcemia, severe liver insufficiency.
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