2015年8月4日星期二

Stem Cell Therapy for Diabetic Nephropathy


Diabetic nephropathy is secondary to diabetes. It is a significant cause of kidney failure in clinic. Stem Cell Therapy brings new hope for people with the disease.

What is Stem Cell Therapy?

Stem cells are the primitive cells in human body. It is featured with capacity of differentiation and regeneration. The biological functions of stem cells is to repair and regenerate damaged cells. Stem cell therapy exploits this function by administering these cells systematically and in high concentrations directly into the damaged tissue. Stem cells can differentiate into new cells and tissues to replace those impaired ones.

Stem Cell Therapy refers to infusion of stem cells into body just like intravenous infusion . As no surgery is intervened, it causes no trauma on body at all.

How does Stem Cell Therapy work to treat diabetic nephropathy?

In diabetes, islet cells become impaired and fail to produce insulin normally as before, thus leading to high blood sugar level. Over time, high blood sugar and a series metabolic disorders like sugar metabolic disorder, lipid metabolic disorder etc. Consequently, kidneys will become involved adversely.

Kidneys are composed of five types of renal intrinsic cells. In normal condition, these cells work to maintain renal functions. However, in diabetic nephropathy, these cells become impaired and fail to function normally.

Therefore, to treat diabetic nephropathy, the root treatment goal is to restore those impaired renal intrinsic cells and islet cells. After diabetes is controlled, it will not cause new damage to kidneys.

After stem cells are infused into body, for the homing capacity, they will reach the impaired organs and differentiate into the cells that body needs. Hence, the new cells can replace those impaired islet cells and renal intrinsic cells. As a result, the kidneys and islet will function better.

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