2014年10月16日星期四

Chronic renal failure, development of which phase?

Recently, a lot of chronic renal failure, patients want to know, how disease sub-type? This is a lot of patient concern, so let's take a look, and hope to patients to help.
Kidney failure treatment network of experts pointed out that, in chronic renal failure disease, it is a lot to see, it's a disease, but the clinical it is not an independent disease is a variety of reasons-induced kidney damage progress of deterioration of the developed end stage, kidney function close to normal around 10 per cent, with a series of syndrome, a relatively long The course of the disease, according to their function, kidney function, damage of kidney function is not fully compensate for a period, the kidney function is not lost substitution for a period also known as nitrogen quality of blood-term, renal failure-term, end-term also known as uremia. And chronic renal failure for many, many reasons, so should be brought to patients, friends attention.
In General, in clinical, chronic renal failure patients based on the disease development, chronic renal failure sub-model has four phases : a compensation period : in substitution for a period of time, nephrotic syndrome patients, blood creatinine effectiveness of 178 micro-Moore, blood urea nitrogen less than 9 mmol per liter, the creatinine clearance is lower, and generally no clinical symptoms. . Lost substitution for term : blood urea nitrogen in the ninth mmol per litre, blood creatinine reached 178 micro-Moore, creatinine clearance per minute at 25-50 mg. In addition to mild GI symptoms and anaemia symptoms, chronic renal failure patients the night to pee increased no obvious discomfort symptoms, but the infection, blood pressure fluctuations, food, protein, tired, symptoms will increase in this period is also known as the nitrogen quality of blood, period.
This clinical is still the most common renal failure sub-model : in this time of chronic renal failure patients, blood creatinine per liter 221-442μmoL, blood urea nitrogen per litre for 17.9-21.4 mmol, endogenous creatinine clearance rate per minute for 10-25 ml. Most of the patients to the more obvious anemia and digestive symptoms, mild calcium, phosphorus metabolic abnormalities or metabolic acidosis., but there was no obvious water, salt, metabolic disorders, known as uremia, an early stage. Uremia : blood urea nitrogen per liter greater than 21.4 mmol, blood creatinine per liter greater than 442 micro-molar. There is often a variety of uremia symptoms, such as marked anaemia, severe vomiting, nausea and a variety of neurological complications, and even coma. Clear water-salt metabolism and acid-base balance disorder, blood creatinine per minute greater than the 707 micro-Moore, creatinine clearance less than ten milliliters of time, known as uremia late symptoms.

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