There are two primary membranous nephropathy serious complications

Insidious onset idiopathic membranous nephropathy, a small number of precursors after the onset of infection. 15% ~ 20% in asymptomatic proteinuria as the first symptom, 80% with nephrotic syndrome, a non-selective proteinuria. Accounting for about 60 percent of adult microscopic hematuria, children may have gross hematuria, but rarely see red tube. Early blood pressure were normal, with the progression of about 50% hypertension, kidney disease can be alleviated with the disappearance. Patients need to be wary of membranous nephropathy complications include the following two:

A combined anti-GBM crescentic glomerulonephritis

Due to the basement membrane damage, membrane antigen exposure or release can lead to the formation of anti-basement membrane antibodies. May be detected in serum anti-basement membrane antibodies, anti-neutrophil antibodies (ANCA). So, if medically stable patients with renal dysfunction and rapid rapidly progressive glomerulonephritis like performance, this should be highly vigilant complications possible.

Second, the high-clotting disorders and renal vein thrombosis

Due to increased levels of blood clotting factors nephrotic syndrome, platelet adhesion and cohesion enhanced antithrombin Ⅲ and antiplasmin activity increased, and produce high-clotting disorder. Applications can promote hormone hypercoagulable. The incidence of renal vein thrombosis of the disease is about 50%, more common in chronic type may be no obvious symptoms, but make nephrotic syndrome worse. Acute type can be manifested as sudden back pain, often more severe, accompanied by pain in the kidney area that is hit, hematuria, often gross hematuria, urinary white blood cells, a sudden increase in proteinuria, hypertension and acute renal dysfunction, bilateral renal vein thrombosis even oliguria and acute renal failure, there may be side kidney disease increases. In chronic renal tubular dysfunction may have a performance such as: renal glucosuria, amino acids in urine, renal tubular acidosis. In addition, pulmonary embolism. Extrarenal thrombosis can also occur such as: brain, heart, leg and so on. The need for a clear diagnosis of renal vein or renal artery angiography, CT radioactive renogram and also help diagnosis.


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