How renal dysfunction medication

Renal insufficiency, the use of antibiotics to select the general principles are:

① infection, should test the choice of antibiotics based on culture and sensitivity;

② no obvious signs of infection were not given antibiotics;

③ Select non-toxic or less toxic to the kidneys and not because of drug accumulation and cause serious damage to other organs of antibiotics.

On the adjustment of the dose should note the following:

Antibiotics (1) should not be applied: Vanguard ADM positive, tetracycline, vancomycin, neomycin.


(2) the basic need to adjust the doses of antibiotics: erythromycin, doxycycline and rifampin.

(3) the need to reduce the dose of antibiotics: amino sugar type antibiotics, tobramycin, neomycin, polymyxin, and Pioneer.

(4) The need for appropriate dose adjustment antibiotics: lincomycin, penicillin family. Chloramphenicol, amphotericin B and so on. Typically reduced to a normal amount of from about 1/2 to 1/3.