2014年12月10日星期三

By identifying renal blood urea nitrogen

What is the blood urea nitrogen, blood urea nitrogen check what is the point?

Urea is the major end products of nitrogen metabolism in human proteins. Deamination of amino acids to produce NH3, and C02, both urea synthesis in the liver, metabolism of urea per gram of protein 0.3g. Urea nitrogen content of 28/60, almost half. Renal excretion of urea is usually the main organ of urea from the glomerular filtration can be reabsorbed in the tubules of each segment, but renal tubular reabsorption of urine flow rate, the faster the less, that reached a maximum clearance. And serum creatinine, as in early renal dysfunction, blood urea nitrogen in the normal range. When the glomerular filtration rate dropped to 50 percent below normal, blood urea nitrogen concentration was increased rapidly.

Under normal circumstances, blood urea nitrogen and creatinine ratio (BUN / Scr) value of about 10, high-protein diet, high catabolic state, water shortages, renal ischemia, hypovolemia, and some acute glomerulonephritis, are The ratio can increase, even up to 20 to 30; and a low-protein diet, liver disease often makes ratio decreased, then you can be called low azotemia.

BUN normal adult fasting for 3.2-7.1mmol / L (9-20mg / d1). Various renal parenchymal lesions, such as glomerulonephritis, interstitial nephritis, acute and chronic renal failure, kidney disease and destructive footprint can make blood urea nitrogen increased. Multi-renal factors may also cause elevated blood urea nitrogen, and external factors such as to exclude one kidney, BUN), 21.4mmol / L (60mg / d1) is the diagnostic criteria uremia.

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