2014年7月14日星期一

How to determine hypertensive renal damage?

The severity of kidney damage caused by hypertension and essential hypertension, duration is closely related to the clinical findings of hypertensive nephropathy mainly benign renal arteriosclerosis.
Incidence of benign renal arteriosclerosis and hypertension severity, and duration were positively correlated. General primary hypertension for 5 years to 10 years, there may be mild to moderate renal atherosclerosis, the gradual emergence of tubules and functional changes.

Diagnosis of hypertension benign arteriolar nephrosclerosis major clinical basis:
① there is a genuine and sustained hypertension; ② age of onset of hypertension between 25 to 45 years, more than 10 years in duration, the higher the greater the incidence of age; ③ other organ damage associated with hypertension, such as: left ventricular hypertrophy, retinal vascular disease, etc.; prominent clinical manifestations ④ as tubulointerstitial damage, such as nocturia, urinary dysfunction concentration, some patients may manifest as proteinuria and a small amount of red blood cells, few showed elevated serum creatinine; ⑤ kidney B-ultrasound, kidney or both kidneys sizes shrink, grainy surface uneven; ⑥ exclude patients with primary renal disease associated with hypertension; ⑦ biopsy showed pathological changes in renal arteriosclerosis based. Essential hypertension-induced kidney damage, usually first appear abnormal urine test based on clinical, rather then high blood pressure, and they should consider the primary renal disease associated with hypertension; After hypertension occur again if the first urine abnormalities in primary the possibility of kidney disease caused by hypertension big damage.

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