IgA nephropathy

IgA nephropathy was first described in 1968 by the Berger, it is also called Berger's disease. Tenth International Conference on Kidney Disease in July 1987 has been recognized as the highest incidence of the disease is the leading one ESRD most common primary glomerulonephritis, about a primary glomerulonephritis / 3. The disease is more common in young people, mostly in the incidence of 20 to 30 years old, male and female incidence ratio of 1:1.
IgA nephropathy is a common pathological features of a class of immune diseases. Where in glomerular mesangial obvious granular IgA deposition, mesangial cells and mesangial matrix, mesangial area expansion, in addition to other secondary side of IgA deposition diseases such as nephritis, lupus nephritis , hepatitis B associated glomerulonephritis, when alcoholic liver disease, be included in the scope of IgA nephropathy, the diagnosis of this disease depends mainly on biopsy.
The inclusion of this disease over the past occult nephritis, and now that it is an independent glomerular disease, and prove that it is not a benign disease, about 15% to 20% of patients with chronic renal function may occur in 10 years failure.