Factors of diabetic nephropathy occurs in uremia

1 , smoking, smoking is a factor leading to diabetic nephropathy in type 2 diabetes occurred . Studies have indicated that , in patients with type 2 diabetes diagnosed earlier , the incidence of proteinuria in a lot of smokers was 8.2 % in patients who smoked was 7.3% , only 2.1 % of never smokers , smoking can lead to vascular compression , but also with blood platelet function abnormalities swap efficiency , thereby increasing vascular damage in diabetic patients .



2 , genetic background , it has long been realized that the incidence of diabetic nephropathy and significant extent there are differences . And in the unity of race , the onset of diabetic nephropathy family gathered there necessarily sexual . Clinically, we often find that some of the long-term manipulation of the patient's blood sugar is better, but still occur in diabetic nephropathy , diabetic patient's blood sugar and some manipulation is not fantasy , but do not occur in diabetic nephropathy , it is a great factor in patients with genetic association.



3 , abnormal lipid metabolism , and , like all the other chronic complications of diabetes , hyperlipidemia is a factor. Clinically, we often invention , the presence of diabetic nephropathy in patients with abnormal lipid metabolism evident . It is related to poor blood sugar grasp , and with the increased level of kidney damage . Promote the progress of high cholesterol diabetes nephropathy , diabetes is increased blood lipids clutter, creating a vicious cycle .



4 , hypertension, high blood pressure is a major factor in progression of diabetic nephropathy . Hypertension can accelerate the progress of diabetic nephropathy and renal dysfunction that occurs with advanced renal failure, uremia. Patients with type 1 diabetes , high blood pressure is secondary to local diabetes . In patients with type 2 diabetes , high blood pressure often occurs before diabetes.



5 , hyperglycemia, as early as 1985. WHO study group on diabetes research , patients with diabetic nephropathy important fasting glucose greater than 7.8 in mmol / l occur. A series of metabolic disorders that occur hyperglycemia in diabetic nephropathy , and ultimate progression to advanced renal failure , an important factor in uremia . Click Ask the Experts