Focal segmental glomerulosclerosis (FSGS) in children and adults with nephrotic syndrome (NS) common primary glomerular disease . Histopathological features is its segmental glomerular scarring, with or without the formation of foam cells and glomerular capillary adhesion . Is the only part of the focal glomerular be involved ( glomerular involvement < 50% ) ; segmental glomerular leaflets is a portion to be involved ; glomerular sclerosis refers to the glass-like stage renal changes or scarring . Other pathological changes include : diffuse mesangial cell proliferation, glomerular capillary collapse and focal degeneration . FSGS by a known cause (HIV or diamorphine ) caused in patients with idiopathic pathological changes similar. Focal sclerosing glomerulonephritis and FSGS are different concepts , the former may be either express or nonspecific idiopathic FSGS hair can also be qualitative performance among other glomerular diseases, or small tube . The disease mostly occurs in children and adolescents , men slightly more than women , mainly for children with primary nephrotic syndrome , a common histological changes are minimal change based. Adults are mainly focal segmental glomerulonephritis , membranous nephropathy and minimal change .
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