2014年1月24日星期五

IgA nephropathy will develop chronic renal failure do?

 IgA nephropathy will develop chronic renal failure do? IgA nephropathy is a special type of glomerulonephritis, pathological changes : differences in the extent of the lesion is large, early lesions minor , were focal , only a few have mild glomerular Department film and stage widened hyperplasia , focal proliferative changes may develop focal sclerosis. IgA nephropathy in renal fibrosis if not treated at an early increase, finally becoming chronic renal failure.
There are significant regional differences in the prognosis of IgA nephropathy , while closely associated with the clinical manifestations and pathological changes. Most of the slow progress of the disease . With IgA nephropathy prognostic factors are: 1 , male patients , older age of onset and poor prognosis . 2 , persistent microscopic hematuria with proteinuria compared with poor prognosis of recurrent hematuria 3 , moderate to severe proteinuria often prompt severe glomerular lesions will eventually develop renal insufficiency , poor prognosis. 4 , hypertension particularly difficult to control hypertension renal damage prompted heavy , poor prognosis , rapid decline in renal function . However, most patients with renal dysfunction speed inconsistent. 5 , a great impact on the prognosis of pathological changes . Serious proliferation, glomerular sclerosis, crescent formation , capillary wall damage , interstitial fibrosis and vascular damage is an indication of poor prognosis of IgA nephropathy .
IgA deposition site and the prognosis is related to the glomerular capillary wall has IgA deposition than those purely mesangial IgA deposition by pathological changes in weight , the prognosis is poor. Fibronectin deposition with poor prognosis . Chronic Renal Failure Chronic renal means or chronic kidney disease involving the kidney caused by systemic disease decreased , and various clinical symptoms and the resulting metabolic disorders consisting syndrome.
IgA nephropathy will develop chronic renal failure do ? IgA nephropathy will develop chronic renal failure, just a matter of time , with these factors. Adult children with chronic renal failure, much higher than the common , mostly with diagnosed 10 - 20 years later. Therefore , IgA nephropathy kidney to early to the regular hospital for kidney treatment guidelines science.

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