Renal failure - renal failure, renal failure characteristics

Early diagnosis of drug-related ARF is a key determinant of patient prognosis . Therefore, patients with unexplained acute renal failure attention detail about medication history, allergies extremely important for suspected cases must be immediately disabled the dynamic observation of suspicious drugs in a timely manner when necessary biopsy is often helpful in diagnosis .
In the case , a total of 125 cases were diagnosed by renal biopsy . Analysis, need to rely on biopsy diagnosed patients, mostly atypical clinical manifestations , the original foundation or exist glomerular disease and renal interstitial renal tubular lesions ;
And for those more typical manifestations of acute tubular necrosis or acute interstitial nephritis , as long as the alert physicians to diagnose clinically .
However, in these patients, after administration of systemic allergic manifestations rarely , drug fever incidence rate was 4.8% , rash incidence rate was 16.7 %. Because of its clinical manifestations are not specific, and the lack of specific and sensitive detection methods , easily mistaken , missed clinically .
Hyponatremia and hypernatremia : Due to vomiting, diarrhea, loss of too much sodium , reduce tubular sodium reabsorption , prone to hyponatremia. When such a sudden increase in sodium intake , prone to water and sodium retention , hypertension, edema and heart failure.
Hyperkalemia and hypokalemia : oliguric renal excretion of potassium decreased. Increased body catabolism , metabolic acidosis, extracellular potassium + to transfer, use retention of potassium-sparing diuretics or angiotensin converting enzyme inhibitors , can cause severe hyperkalemia