What is the occult glomerulonephritis?

Acute rapidly progressive glomerulonephritis (referred to as rapidly progressive glomerulonephritis) is a group of progression of the disease onset, proteinuria, hematuria, edema, hypertension and other symptoms in a few days, or a sharp deterioration in the next few months several weeks, oliguria, no urine, renal failure, glomerular nephritis poor prognosis in general. The disease diagnosis must rely on biopsy, the diagnosis is the most important body stuffed in a large crescent renal capsule, accounting for more than 50% of glomerular involvement, accompanied by glomerular capillary regional fiber necrosis, ischemia and thrombosis , mesangial matrix, renal tubular necrosis, renal interstitial fibrosis, inflammatory cell infiltration and other changes. Immunofluorescence this disease is divided into three types: Ⅰ type of anti-glomerular basement membrane antibody nephritis, showed IgG and complement C3 was deposited along the lines like the glomerular capillary wall; Ⅱ type of immune complex-type nephritis, showed IgG and C3 along mesometrium capillary walls showed granular deposition; Ⅲ type of glomerular no IgG deposition, or IgG deposition in glomeruli is an irregular sparse focal deposition, with the former difference between the two. The disease with poor prognosis and high mortality, 5-year survival rate of about 25%.