2014年1月1日星期三

How to solve some small problems with nephrotic syndrome treated?


Nephrotic syndrome is due to an increased glomerular filtration membrane permeability , resulting in a large number of plasma proteins from the urine caused by the loss of a clinical syndrome . Clinical features: proteinuria continued for more than two weeks ; hypoalbuminemia ; hyperlipidemia, and varying degrees of edema. There are many treatment methods nephrotic syndrome , but the election of the treatment , there will be many issues to us to consider , such as the treatment of problems encountered , how do we fix it?

1 stick kidney specialist out-patient follow-up, in order to facilitate long-term observation , the best remission after 5 years of follow-up .

2 . Avoid all kinds ( respiratory, gastrointestinal ) infections, recurrent infections lead to kidney failure , frequent recurrence of adverse conditions .

3 In addition to severe edema , but avoid long-term avoid salt , especially in summer , severe cases can cause hyponatremia syndrome and even shock, convulsions. Using low-salt ( 2 g daily ) of commercially available sodium soy sauce containing about 2 grams per 10ml, not only to avoid the phenomenon of hyponatremia , and improve appetite.

4 during the acute phase of treatment suspend immunization .

5 infection should avoid blind use of antibiotics , especially renal toxicity of antibiotics to avoid large doses or unreasonable use of diuretics . Blindly seeking vivre diuretic often brings hypovolemic shock , hypercoagulable state and thrombosis .

6 glucocorticoid therapy was first used , there are strict regulations dose , treatment should not be half-way on their own reduction or withdrawal. In some cases, highly sensitive to the hormone , a decrease in urinary protein after treatment , the swelling disappeared , this time as " mend stopped " , a look at the phenomenon of blind surface reduction or withdrawal often cause recurrent disease or relapse.

7 periodic review of blood biochemistry ( renal function ) , urine to determine drug effects and changes in the disease and recovery, easy to adjust treatment follow-up .

Edema completely subsided , urine protein disappeared many times , can be called normal biochemical complete remission of nephrotic syndrome .

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