2014年1月9日星期四

Slightly higher than the upper limit of serum creatinine, say what? How to treat, health care?


The ultimate goal of laboratory tests is to determine whether the test result is normal, and therefore the laboratory tests should have normal or normal range. Normal test results to judge the long-established concept, but its meaning is unclear, due to the precise concept gradually be eliminated, and now on the normal single laboratory has been replaced by a reference value or reference range .

Then , the reference value or reference range is how to determine it ? It is not suffering researchers corresponding disease inspection corresponding normal population , using statistical methods and the statistical test results , take the range of 95% or 97.5% as the reference range. In serum creatinine of renal function , for example, the reference range is 44 ~ 133μmol / L, serum creatinine that is to say the vast majority of normal renal function and the distribution of population in 44 ~ 133μmol / L. If your blood creatinine test results were significantly higher than 133μmol / L, you are prompted to renal function may be an exception.

Note that the test results below or above the reference range , is not necessarily suffering from a pathological condition or disease . Because a person 's test results affected by many factors , such as strenuous exercise , fever , chills , and mental stress , will make people appear protein in the urine , and higher than the upper limit of the reference range proteinuria 150mg/24h. This urinary protein is a normal phenomenon of the human body , known as physiological proteinuria , should be distinguished from pathological proteinuria and renal disease. Because of muscular athlete , creatine kinase CK levels which will significantly above the reference range , does not mean that its prevalence . There are many such examples. In fact , tests are only one aspect of disease information , with the test results , the doctor and then combined with information on a comprehensive analysis of symptoms, signs , and other laboratory examinations , etc., in order to make the right judgments.

In addition, the test results of different age or gender , can not be judged by the same reference range. Because of different ages , gender differences exist reference range , to determine if a range , often draw the wrong conclusions , misleading clinical judgment . For example, children born bilirubin , erythrocytes, hemoglobin levels and adults vary greatly ; alkaline phosphatase levels of children and adolescents is generally higher than adults ; elderly creatinine clearance rate will naturally be reduced ; Men creatine kinase , acid phosphatase than women , and so on .

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