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Then , the reference value or reference range is how to determine it ? It is not suffering researchers corresponding disease inspection corresponding normal population , using statistical methods and the statistical test results , take the range of 95% or 97.5% as the reference range. In serum creatinine of renal function , for example, the reference range is 44 ~ 133μmol / L, serum creatinine that is to say the vast majority of normal renal function and the distribution of population in 44 ~ 133μmol / L. If your blood creatinine test results were significantly higher than 133μmol / L, you are prompted to renal function may be an exception.
Note that the test results below or above the reference range , is not necessarily suffering from a pathological condition or disease . Because a person 's test results affected by many factors , such as strenuous exercise , fever , chills , and mental stress , will make people appear protein in the urine , and higher than the upper limit of the reference range proteinuria 150mg/24h. This urinary protein is a normal phenomenon of the human body , known as physiological proteinuria , should be distinguished from pathological proteinuria and renal disease. Because of muscular athlete , creatine kinase CK levels which will significantly above the reference range , does not mean that its prevalence . There are many such examples. In fact , tests are only one aspect of disease information , with the test results , the doctor and then combined with information on a comprehensive analysis of symptoms, signs , and other laboratory examinations , etc., in order to make the right judgments.
In addition, the test results of different age or gender , can not be judged by the same reference range. Because of different ages , gender differences exist reference range , to determine if a range , often draw the wrong conclusions , misleading clinical judgment . For example, children born bilirubin , erythrocytes, hemoglobin levels and adults vary greatly ; alkaline phosphatase levels of children and adolescents is generally higher than adults ; elderly creatinine clearance rate will naturally be reduced ; Men creatine kinase , acid phosphatase than women , and so on .
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